SOILGUARD envisages a future where soil biodiversity conservation and the environmental, economic and social well-being of EU biogeographical regions are guaranteed. Unsustainable management and climate change are increasing land degradation and threatening soil biodiversity. Urgent action is required to mainstream sustainable soil management practices and the perception of soil biodiversity as a key nature-based solution to face land degradation and climate change stressors. The efficacy of this call to action depends on addressing